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K + and Na + follow their concentration gradients (K + out of the cell, Na + in). Na + concentration is much higher extracellularly.K + concentration is much higher intracellularly.The most important difference between ICF and ECF is the relative concentration of cations: The biochemical balance between ICF and ECF is very tightly controlled as many crucial physiological processes depend on its composition. It includes CSF, exocrine secretions and gastrointestinal secretions. * Transcellular fluid is the name given to fluids in the body that are not contained within the ICF or ISF/plasma (ECF) compartments. These two compartments are separated by cell membranes, and are very different in their composition (i.e. Extracellular fluid (ECF) – itself can be divided into:.Intracellular fluid (ICF) – the fluid within cells which accounts for 65% of total body weight.Water makes up 50-70% of body mass – approximately 42L in a 70kg person. The osmolality of plasma = 290 mosmol/kg H 2O Body Water Compartments Osmolality is the preferred expression of physiologists because it is independent of temperature and pressure. Osmolality – osmotic concentration per volume of solution (osmol/kg H 2O).Osmolarity – osmotic concentration per mass of solvent (osmol/L).It can be expressed as ‘osmolarity’ or ‘osmolality’: Osmotic potential is determined by the number of osmotically active particles per litre.
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